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1.What is the Doxifluridine ?
White Solid
ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.
2.What is the CAS number for Doxifluridine ?
The CAS number of Doxifluridine is 3094-09-5.
3.What are another words for Doxifluridine ?
Synonyms?for?Doxifluridine 3094-09-5:5-Fluoro-5'-deoxyuridine;5-Fluorodesoxyuridine;5'-DFUR;5'-Deoxy-5-fluorouridine;5'-dFUrd;Flutron;Furtulon;Ro 21-9738;Uridine,5'-deoxy-5-fluoro-;Doxyflruidine;
4.What is Doxifluridine (3094-09-5) used for?
antineoplastic, pyrimidine antimetabolite
InChI:InChI=1/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6?,8?/m1/s1
Relevant articles related to Doxifluridine:
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Article |
Source |
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Uracil nucleoside derivative and method for preparing deoxyuridine drug by using same (by machine translation) |
- Paragraph 0068-0072, (2020/05/14) |
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Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism |
Downey, A. Michael,Pohl, Radek,Roithová, Jana,Hocek, Michal supporting information, p. 3910 - 3917 (2017/03/27) |
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Rapid continuous synthesis of 5′-deoxyribonucleosides in flow via Br?nsted acid catalyzed glycosylation |
Shen, Bo,Jamison, Timothy F. supporting information; experimental part, p. 3348 - 3351 (2012/08/08) |
5.Buy Doxifluridine with the best price .
Jinhe Chemical Co., Ltd. is a quality supplier of Doxifluridine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Doxifluridine 3094-09-5.
