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Factory Sells Best Quality 2-Acetylbenzo[b]thiophene 22720-75-8 with GMP standards
- Molecular Formula: C10H8OS
- Molecular Weight: 176.239
- Appearance/Colour: white to light yellow crystal powder
- Vapor Pressure: 0.00087mmHg at 25°C
- Melting Point: 86-88 ºC
- Refractive Index: 1.646
- Boiling Point: 304.5 ºC at 760 mmHg
- Flash Point: 138 ºC
- PSA： 45.31000
- Density: 1.219 g/cm3
- LogP: 3.10390
2-Acetylbenzo[b]thiophene(Cas 22720-75-8) Usage
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Synthesis Reference(s) |
Synthetic Communications, 23, p. 743, 1993 DOI: 10.1080/00397919308009834 |
InChI:InChI=1/C10H8OS/c1-7(11)10-6-8-4-2-3-5-9(8)12-10/h2-6H,1H3
22720-75-8 Relevant articles
Inhibitors of tissue-nonspecific alkaline phosphatase: Design, synthesis, kinetics, biomineralization and cellular tests
Debray, Julien,Chang, Lei,Marquès, Stéphanie,Pellet-Rostaing, Stéphane,Le Duy, Do,Mebarek, Saida,Buchet, René,Magne, David,Popowycz, Florence,Lemaire, Marc
, p. 7981 - 7987 (2013)
Chronic kidney disease (CKD) is associat...
Synthesis of the 5-lipoxygenase inhibitor zileuton from thiophenol
Basha,Brooks
, p. 1293 - 1294 (1993)
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Synthesis of substituted 2-mercaptobenzaldehydes and 2-substituted benzo[b]thiophenes
Gallagher, Timothy,Pardoe, David A.,Porter, Roderick A.
, p. 5415 - 5418 (2000)
Simple and rapid single-pot preparations...
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Forsyth,D.A.,Olah,G.A.
, p. 5309 (1979)
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Investigation on the one-step preparation of 2-substituted benzo[B]thiophenes
Zhao, Qian,Qian, Chao,Chen, Xin-Zhi
, p. 873 - 878 (2013)
A convenient and efficient synthesis of ...
Overcoming Electron-Withdrawing and Product-Inhibition Effects by Organocatalytic Aerobic Oxidation of Alkylpyridines and Related Alkylheteroarenes to Ketones
Wang, Hua,Liu, Jie,Qu, Jian-Ping,Kang, Yan-Biao
, p. 3942 - 3948 (2020/03/23)
An organocatalyzed aerobic benzylic C-H ...
Iron–PNP-Pincer-Catalyzed Transfer Dehydrogenation of Secondary Alcohols
Budweg, Svenja,Wei, Zhihong,Jiao, Haijun,Junge, Kathrin,Beller, Matthias
, (2019/05/10)
The well-defined iron PNP pincer complex...
Hydrogen bond donor solvents enabled metal and halogen-free Friedel–Crafts acylations with virtually no waste stream
Liu, Guangchang,Xu, Bo
supporting information, p. 869 - 872 (2018/02/09)
We have developed a metal and halogen-fr...
Copper-catalyzed synthesis of 2-acylbenzo[: B] thiophenes from 3-(2-iodophenyl)-1-arylpropan-1-ones and potassium sulfide under aerobic conditions
Zheng, Zhilei,Chen, Liang,Qian, Cheng,Zhu, Xiaoming,Yang, Yuzhong,Liu, Jianbing,Yang, Yuan,Liang, Yun
, p. 8020 - 8024 (2018/11/23)
A method was developed for the synthesis...
22720-75-8 Process route
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53606-33-0
2-(ethylsulfanyl)benzenecarbaldehyde
-
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78-95-5
chloroacetone
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![2-acetyl benzo[b]thiophene](/upload/2026/4/c071974527e146d0837e57132c66b3d7_122e7fe1-abdd-4588-bdb8-d92b4995f54f.png)
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22720-75-8
2-acetyl benzo[b]thiophene
| Conditions | Yield |
|---|---|
|
With
calcium oxide;
In
acetone;
at 59 ℃;
|
100%
|
|
With
calcium oxide;
for 3h;
Reflux;
|
-
-
127-19-5,116057-81-9
N,N-dimethyl acetamide
-
![Benzo[b]thiophene](/upload/2026/4/be95ecc5b05a4e1eb3252db64f6b44e4_d99ce2cf-c324-4e64-ad5a-103ffafbb171.png)
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95-15-8,11095-43-5
Benzo[b]thiophene
-
-
22720-75-8
2-acetyl benzo[b]thiophene
| Conditions | Yield |
|---|---|
|
Benzo[b]thiophene;
With
n-butyllithium;
In
diethyl ether; hexane;
at -78 ℃;
for 1.5h;
Reflux;
N,N-dimethyl acetamide;
In
diethyl ether; hexane;
for 2h;
Reflux;
|
78%
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 - 22 ℃;
|
35%
|
22720-75-8 Upstream products
-
50779-55-0
benzothiophen-2-yllithium
-
108-24-7
acetic anhydride
-
95-15-8
Benzo[b]thiophene
-
130966-65-3
2-(hydroxymethyl)thiophenoxyacetone
22720-75-8 Downstream products
-
6314-28-9
benzo[b]thiophene-2-carboxylic acid
-
97511-06-3
1-(benzo[b]thiophen-2-yl)-2-bromoethanone
-
399-80-4
1-benzo[b ]thiophen-2-yl-4,4,4-trifluoro-butane-1,3-dione
-
83656-90-0
1-Benzo[b]thiophen-2-yl-1-[2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-ethanol
