Product
Buy high quality and low price 3-Acetylthio-2-methylpropanoic acid 33325-40-5 now
- Molecular Formula: C6H10O3S
- Molecular Weight: 162.21
- Appearance/Colour: White solid
- Vapor Pressure: 0.0013mmHg at 25°C
- Melting Point: 55-57 °C
- Boiling Point: 276.5 °C at 760 mmHg
- PKA: 4.22±0.10(Predicted)
- Flash Point: 121 °C
- PSA： 79.67000
- Density: 1.213 g/cm3
- LogP: 0.98680
3-Acetylthio-2-methylpropanoic acid(Cas 33325-40-5) Usage
|
Purification Methods |
Distil the acid under high vacuum and recrystallise it from *C6H6. [Fredga & Mastersson Chem Abstr 38 3616 1944.] |
InChI:InChI=1/C6H10O3S/c1-4(6(8)9)3-10-5(2)7/h4H,3H2,1-2H3,(H,8,9)/p-1/t4-/m1/s1
33325-40-5 Relevant articles
Preparation method of 3-acetylthio-2-methylpropionic acid
-
Paragraph 0076-0079; 0083-0085, (2020/05/02)
The invention discloses a preparation me...
Tetrahydroisoquinoline derivative and application thereof
-
Paragraph 0033; 0041, (2016/10/27)
The invention belongs to the technical f...
SN2-type nucleophilic opening of β-thiolactones (thietan-2-ones) as a source of thioacids for coupling reactions
Crich, David,Sana, Kasinath
scheme or table, p. 3389 - 3393 (2009/10/02)
β-Thiolactones monosubstituted in the 3-...
Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase
Ghizzoni, Massimo,Haisma, Hidde J.,Dekker, Frank J.
scheme or table, p. 4855 - 4861 (2010/01/16)
Development of small molecule inhibitors...
33325-40-5 Process route
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-
26473-47-2
2-methyl-3-sulfanylpropanoic acid
-
-
108-24-7
acetic anhydride
-
-
33325-40-5
3-(acetylthio)-2-methylpropanoic acid
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
water;
at 0 - 5 ℃;
Reagent/catalyst;
Inert atmosphere;
|
91%
|
-
-
79-41-4,25087-26-7,50867-57-7
poly(methacrylic acid)
-
-
507-09-5
tiolacetic acid
-
-
33325-40-5
3-(acetylthio)-2-methylpropanoic acid
| Conditions | Yield |
|---|---|
|
In
tetrahydrofuran;
Heating;
|
99%
|
|
With
hydroquinone;
at 90 ℃;
for 1h;
|
89.2%
|
|
In
hexane;
for 5h;
Reflux;
|
80%
|
|
1.) 5 deg C, 15 min, 2.) reflux, 1 h, 3.) RT, 6 d;
|
77.5%
|
|
|
|
|
In
3-(acetylthio)-2-methylpropanoic acid;
|
|
|
In
3-(acetylthio)-2-methylpropanoic acid;
|
|
|
In
3-(acetylthio)-2-methylpropanoic acid;
|
|
|
In
cyclohexane;
Reflux;
|
33325-40-5 Upstream products
-
79-41-4
poly(methacrylic acid)
-
507-09-5
thioacetic acid
-
507-09-5
tiolacetic acid
-
26473-47-2
2-methyl-3-sulfanylpropanoic acid
33325-40-5 Downstream products
-
106014-16-8
2,5-dimethyl-3-thia-adipic acid
-
26473-47-2
2-methyl-3-sulfanylpropanoic acid
-
4131-76-4
methyl 3-mercapto-2-methyl-propionate
-
97101-46-7
methyl L-(+)-3-acetylthio-2-methylpropionate
